Respiratory virus isolates made at the National Institute for Virology
from 1982 to 1991 were studied. An active virus surveillance programm
e, 'viral watch', which recruits throat swab specimens from a network
of monitoring centres - mainly in the Witwatersrand and Vereeniging ar
ea with one centre in Middelburg - that represent a cross-section of t
he population, provided 68% of the specimens and 74% of the isolates,
with an isolation rate of 25,5%. This was significantly higher than th
at of routine specimens (17,7%). Of the 966 isolates, influenza viruse
s accounted for 527 (54,7%), para-influenza for 122 (12,6%), respirato
ry syncytial virus for 34 (3,4%) and adenovirus for 106 (11,0%). Influ
enza viruses showed a definite seasonal peak between June and August w
hereas the other viruses, although they showed a winter predominance,
were isolated throughout the year. An active virus surveillance progra
mme is particularly valuable in monitoring respiratory virus epidemiol
ogy in the population.