PROTECTION OF PHOSPHATE WITH THE 9-FLUORENYLMETHYL GROUP - SYNTHESIS OF UNSATURATED-ACYL PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE

Authors
WATANABE Y NAKAMURA T MITSUMOTO H
Citation
Y. Watanabe et al., PROTECTION OF PHOSPHATE WITH THE 9-FLUORENYLMETHYL GROUP - SYNTHESIS OF UNSATURATED-ACYL PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE, Tetrahedron letters, 38(42), 1997, pp. 7407-7410
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
42
Year of publication
1997
Pages
7407 - 7410
Database
ISI
SICI code
0040-4039(1997)38:42<7407:POPWT9>2.0.ZU;2-8
Abstract
Alkyl di-(9-fluorenylmethyr) phosphates obtained via phosphitylation w ere found to be suitable for protection of phosphoric monoesters, whic h were generated by treatment of the triesters with DBU or triethylami ne. This strategy and a hydroxyl protecting group, 2-[2-(levulinoyloxy )ethyl]benzoyl were applied to synthesis of a dioleoyl analog of PI(4, 5)P-2. (C) 1997 Elsevier Science Ltd.