HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF CIS-TRANS ISOMERS OF PROLINE-CONTAINING DIPEPTIDES .3. COMPARATIVE-STUDIES WITH DIFFERENT STATIONARY PHASES

Authors
WUTTE A GUBITZ G FRIEBE S KRAUSS GJ
Citation
A. Wutte et al., HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF CIS-TRANS ISOMERS OF PROLINE-CONTAINING DIPEPTIDES .3. COMPARATIVE-STUDIES WITH DIFFERENT STATIONARY PHASES, Journal of chromatography, 677(1), 1994, pp. 186-191
Citations number
12
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of chromatography → ACNP
Volume
677
Issue
1
Year of publication
1994
Pages
186 - 191
Database
ISI
SICI code
Abstract
Different stationary phases were compared for their capacity to separa te cis-trans isomers of proline-containing dipeptides for equilibrium and isomerization studies. Both reversed-phase chromatography on an RP -18 or a graphitized carbon phase (Hypercarb S) and ligand-exchange ch romatography on an L-proline-Cu(II) phase can be used effectively to s eparate the cls-trans isomers.