GRANULOMA INGUINALE (DONOVANOSIS) - AN UNUSUAL CAUSE OF OTITIS-MEDIA AND MASTOIDITIS IN CHILDREN

Citation
D. Govender et al., GRANULOMA INGUINALE (DONOVANOSIS) - AN UNUSUAL CAUSE OF OTITIS-MEDIA AND MASTOIDITIS IN CHILDREN, American journal of clinical pathology, 108(5), 1997, pp. 510-514
Citations number
23
Categorie Soggetti
Pathology
ISSN journal
00029173
Volume
108
Issue
5
Year of publication
1997
Pages
510 - 514
Database
ISI
SICI code
0002-9173(1997)108:5<510:GI(-AU>2.0.ZU;2-P
Abstract
Granuloma inguinale (donovanosis) is seen predominantly in adults (it rarely occurs in children) and mainly affects genital skin and mucosa. Infection occurs at other skin and mucosal sites, and hematogenous di ssemination to bone also has been described. The infection responds dr amatically to appropriate antibiotic treatment. We present two cases o f granuloma inguinale occurring in children (8 months and 5 months of age) causing mastoiditis and external ear discharges. A temporal lobe abscess also developed in the 8-month-old child. Subsequent computed t omography scans showed marked improvement in the brain lesion after tr eatment. The second child had a polypoid mass in the middle ear that o n biopsy showed the features of granuloma inguinale. The mother of thi s child had biopsy-proven granuloma inguinale of the uterine cervix. T hese cases indicate that granuloma inguinale can be transmitted during vaginal delivery, and careful cleansing of neonates born to infected mothers is recommended.