THOXYCARBONYL-N-ALKYLAMINOOXY)METHYL]PHENOXYMETHYL POLYSTYRENE - A MULTIPLE SOLID-PHASE APPROACH TO N-ALKYLHYDROXAMIC ACIDS

Authors
MELLOR SL CHAN WC
Citation
Sl. Mellor et Wc. Chan, THOXYCARBONYL-N-ALKYLAMINOOXY)METHYL]PHENOXYMETHYL POLYSTYRENE - A MULTIPLE SOLID-PHASE APPROACH TO N-ALKYLHYDROXAMIC ACIDS, Chemical communications, (20), 1997, pp. 2005-2006
Citations number
14
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
20
Year of publication
1997
Pages
2005 - 2006
Database
ISI
SICI code
1359-7345(1997):20<2005:TP-AM>2.0.ZU;2-3
Abstract
Fluoren-9-ylmethoxycarbonyl-N-alkylhydroxylamines, prepared via K2CO3- catalysed N-alkylation of N,O-bis(tert-butoxycarbonyl)hydroxylamine, u ndergo a highly efficient condensation with 4-[2,4-dimethoxyphenyl(chl oro)methyl]phenoxymethyl polystyrene (PS) to afford thoxycarbonyl-N-al kylaminooxy)methyl]phenoxymethyl PS, which is used for the facile synt hesis of structurally diverse N-substituted hydroxamic acids.