Objective: To present further experience with in-office lysis of intra
uterine adhesions under fluoroscopic control using a specially designe
d catheter. Design: Prospective study. Setting: Medical school-affilia
ted infertility center. Patient(s): Seventeen infertile patients under
going routine gynecoradiologic investigation as part of an initial inf
ertility workup. Intervention(s): The initial hysterosalpingography wa
s performed with a commercially available uterine catheter that seals
off the uterine cavity before injection of contrast. If intrauterine a
dhesions were diagnosed, an immediate attempt at lysis was made using
the catheter's balloon tip or hysteroscopic scissors, which were inser
ted through the main port of the catheter. The procedures were carried
out using a paracervical block or IV analgesia. Main Outcome Measure(
s): Normal uterine cavity after lysis of intrauterine adhesions. Resul
t(s): Seventeen patients underwent lysis of intrauterine adhesions. In
13 patients (9 mild, 3 moderate, and 1 severe), the adhesions were ly
sed successfully (81.2%). Among those, nine procedures were performed
with the balloon and four with scissors. In 4 cases (2 moderate and 2
severe), lysis of adhesions was only partially successful. These proce
dures had to be abandoned prematurely because of patient discomfort be
fore attempting the use of scissors (n = 1), extravasation of dye into
the myometrium making visualization difficult (n = 1), and thick, fib
rotic adhesions that were resistant to scissors (n = 2). Conclusion(s)
: In-office lysis of intrauterine adhesions under gynecoradiologic con
trol can be carried out safely in the majority of patients, using mini
mally invasive techniques. The potential cost savings in comparison wi
th endoscopic procedures, which require utilization of expensive opera
ting room time, are especially relevant in today's cost-conscious mana
ged care environment. Only failures of in-office procedures would reac
h the operating room under the algorithm proposed here. (C) 1997 by Am
erican Society for Reproductive Medicine.