Assessment of asthma severity is important for disease management. Ana
lysis of symptoms past and present, and previous and actual lung funct
ion measurements (including variability) is the usual method of evalua
tion and classification of asthma disease severity and activity. Howev
er. symptoms and lung function alterations are the result of pathophys
iological processes including inflammation in the bronchial wall which
, in chronic phases, precedes the clinical measurements, and are risk
factors for disease progression and worsening. Tools for more precise
determination oi asthma disease processes in the airway wall would be
of importance for prophylactic intervention to avoid chronic damage to
the airways and acute worsenings to occur.