VNTR POLYMORPHISM IN THE BUENOS-AIRES, ARGENTINA, METROPOLITAN POPULATION

Citation
A. Sala et al., VNTR POLYMORPHISM IN THE BUENOS-AIRES, ARGENTINA, METROPOLITAN POPULATION, Human biology, 69(6), 1997, pp. 777-783
Citations number
19
Categorie Soggetti
Genetics & Heredity",Biology
Journal title
ISSN journal
00187143
Volume
69
Issue
6
Year of publication
1997
Pages
777 - 783
Database
ISI
SICI code
0018-7143(1997)69:6<777:VPITBA>2.0.ZU;2-W
Abstract
VNTR loci provide a wealth of information for human genetic research, ranging from gene mapping to paternity testing and forensic identifica tion. In this study we report the construction, validation, and analys is of the first local genetic database for VNTR markers for Argentina. A sample of the metropolitan population of Buenos Aires was typed by means of six VNTR systems. Allele frequencies and expected heterozygos ity were calculated, The sample set was further tested for departures from Hardy-Weinberg equilibrium and power of exclusion. Allele frequen cy distributions are compatible with previously reported data on Cauca sian populations, and no departures from Hardy-Weinberg equilibrium we re detected.