HUMAN N-METHYL-D-ASPARTATE RECEPTOR MODULATORY SUBUNIT HNR2A - CLONING AND SEQUENCING OF THE CDNA AND PRIMARY STRUCTURE OF THE PROTEIN

Authors
FOLDES RL ADAMS SL FANTASKE RP KAMBOJ RK
Citation
Rl. Foldes et al., HUMAN N-METHYL-D-ASPARTATE RECEPTOR MODULATORY SUBUNIT HNR2A - CLONING AND SEQUENCING OF THE CDNA AND PRIMARY STRUCTURE OF THE PROTEIN, Biochimica et biophysica acta. Molecular cell research, 1223(1), 1994, pp. 155-159
Citations number
32
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Molecular cell research → ACNP
ISSN journal
01674889
Volume
1223
Issue
1
Year of publication
1994
Pages
155 - 159
Database
ISI
SICI code
0167-4889(1994)1223:1<155:HNRMSH>2.0.ZU;2-9
Abstract
Several cDNA clones encoding the human N-methyl-D-aspartate receptor m odulatory subunit hNR2A, were isolated from human hippocampus and feta l brain libraries. DNA sequence analysis revealed overlapping clones p ermitting the reconstruction of full-length hNR2A cDNA. The hNR2A cDNA demonstrated an 88-89% nucleotide(nt) identity with the corresponding rodent cDNAs. The nt sequence of hNR2A would encode a 1464-aa protein that has a 95.2% identity with the rodent NR2A subunits.