HIGHLY EFFICIENT PALLADIUM-CATALYZED BORONIC ACID COUPLING REACTIONS IN WATER - SCOPE AND LIMITATIONS

Authors
BADONE D BARONI M CARDAMONE R IELMINI A GUZZI U
Citation
D. Badone et al., HIGHLY EFFICIENT PALLADIUM-CATALYZED BORONIC ACID COUPLING REACTIONS IN WATER - SCOPE AND LIMITATIONS, Journal of organic chemistry, 62(21), 1997, pp. 7170-7173
Citations number
37
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
62
Issue
21
Year of publication
1997
Pages
7170 - 7173
Database
ISI
SICI code
0022-3263(1997)62:21<7170:HEPBAC>2.0.ZU;2-U
Abstract
The ''ligandless'' palladium acetate-catalyzed Suzuki cross-coupling r eaction of ArX with aryl-and vinylboronic acids in water without organ ic cosolvent in the presence of tetrabutylammonium bromide is reported . Aryl bromides give high yields and considerably accelerate the coupl ing, A wide variety of functional groups can be tolerated. Aryl iodide s, however, give. incomplete conversion and aryl triflate coupling sho ws no improvement over reported conditions.