PROPHYLACTIC PERIOPERATIVE TREATMENT IN A PATIENT WITH COLON-CARCINOMA COMPLICATED BY POLYCYTHEMIA-VERA

A patient with colon carcinoma complicated by polycythemia vera (PV) w ho underwent a partial colectomy concomitant with prophylactic periope rative treatment resulting in successful outcome is herein described. Seven weeks after the cessation of the latest exacerbation of PV, a pa rtial colectomy was performed. In order to prevent the development of disseminated intravascular coagulation and thrombotic complications, t he following perioperative treatment was performed: administration of gabexate mesilate (2,000 mg/day), fresh frozen plasma (300 ml/day), he parin (5,000 IU/day) for 7 days and anti-thrombin-III for 4 days, and a potent antibiotic therapy for 12 days and graded elastic bandages ar ound the bilateral lower extremities for 14 days. As a result, an unev entful postoperative course was achieved. The present case suggests th at these treatments are useful in the perioperative management of PV p atients.