ALTERATIONS OF ELECTRICAL CHARGE AND RECE PTORS TO LECTINES MOUSE LYMPHOMA-CELLS SURFACE IN EARLY TERMS AFTER IRRADIATION

Authors
LAVRENCHUK GI VINARCHUK MP BENKOVSKA NP
Citation
Gi. Lavrenchuk et al., ALTERATIONS OF ELECTRICAL CHARGE AND RECE PTORS TO LECTINES MOUSE LYMPHOMA-CELLS SURFACE IN EARLY TERMS AFTER IRRADIATION, Eksperimental'naa onkologia, 19(3), 1997, pp. 202-205
Citations number
12
Categorie Soggetti
Oncology
Journal title
Eksperimental'naa onkologia → ACNP
ISSN journal
02043564
Volume
19
Issue
3
Year of publication
1997
Pages
202 - 205
Database
ISI
SICI code
0204-3564(1997)19:3<202:AOECAR>2.0.ZU;2-7
Abstract
Modifications of structural and functional state of OH-1 mouse lymphom a cells surface in early terms after gamma-irradiation with doses from 0.1 Gy to 10 Gy were studied. For this purpose, the methods of cell s eparation in a two-phase polimer system (dextran-PEG) and cell surface receptors binding with some plant lectines were used. It was revealed the decreased surface electrical charge that reached its maximum defl ection 3 hours after gamma-irradiation. At the same time-dose dependen t expression of irradiated cells, membrane receptors to the lectines o f various specificity was observed.