STATE OF ENDOCRINE AND IMMUNE-SYSTEMS IN OVARIAN-CANCER PATIENTS AND THEIR ROLE IN ANTITUMOR RESISTANCE

The results of investigation of some hormonal homeostatic indices and immunity of patients with disseminated ovarian cancer are given. Initi al relative hyperestrogenization in these patients is detected. Effect ive complex treatment results in the improvement and normalization of hormonal homeostatic indices (increase of FSH, progesterone, essential decrease of prolactin). Data of the immunologic study testify to a si gnificant inhibition of the immune system in ovarian cancer patients i n administration of platidiam, these changes are less expressed in adm inistration of polyplatillen.