A. Rohlmann et al., COMPARISON OF LOADS ON INTERNAL SPINAL FIXATION DEVICES MEASURED IN-VITRO AND IN-VIVO, Medical engineering & physics, 19(6), 1997, pp. 539-546
The loads on internal spinal fixation devices were measured using modi
fied, telemeterized AO-Dick internal fixators. The implants allow meas
urement of the three force components and the three moments acting on
the implant. The modifed fixators were mounted on cadaver spines, and
the implant loads were measured in the intact and postcorpectomy spine
s for differ ent loading modes, including axial compression force, fle
xion, extension, lateral Bending, and torsion. The in vitro experiment
did not consider muscle forces. Modified fixators were also implanted
In three patients, and the implant lends were determined before and a
fter anterior interbody fusion with autologous iliac-crest bone grafts
. The results for different in vitro loading modes were compared with
those in vivo in order to demonstrate the extent to which the in vitro
loads represent the real situation in patients. In several cases, the
implant loads in the in vitro experiment differed strongly from those
measured in patients. For flexion and lateral bending, a tensile axia
l force occasionally was measured in the in vitro experiment, while in
the patients tile axial force was always compressive. Extension was p
redominantly associated with extension bending moments in the in vitro
study but with flexion bending moments in the patients. When muscle f
orces are not considered in the in vitro experiment, the loads on the
fixators may differ significantly from the situation found in patients
. (C) 1997 IPEM. Published by Elsevier Science Ltd.