IMMUNOHISTOCHEMICAL DETECTION OF THE MELANOCORTIN-1 RECEPTOR IN HUMANTESTIS, OVARY AND PLACENTA USING SPECIFIC MONOCLONAL-ANTIBODY

Authors
THORNWALL M DIMITRIOU A XU XL LARSSON E CHHAJLANI V
Citation
M. Thornwall et al., IMMUNOHISTOCHEMICAL DETECTION OF THE MELANOCORTIN-1 RECEPTOR IN HUMANTESTIS, OVARY AND PLACENTA USING SPECIFIC MONOCLONAL-ANTIBODY, Hormone research, 48(5), 1997, pp. 215-218
Citations number
18
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Hormone research → ACNP
ISSN journal
03010163
Volume
48
Issue
5
Year of publication
1997
Pages
215 - 218
Database
ISI
SICI code
0301-0163(1997)48:5<215:IDOTMR>2.0.ZU;2-0
Abstract
We describe the immunohistochemical detection of the melanocortin 1 re ceptor (MC1R) protein in human gonadal tissues using a specific monocl onal antibody. The MC1R was found to be present in Leydig's cells in t estis, in lutein cells in the corpus luteum and in the nucleus of the trophoblastic cells of the placenta. Though it has been speculated ear lier that MC1R is present in gonadal tissues, this is the first report demonstrating the presence of MC1R protein in these cells.