EN-ROUTE TO AN EFFICIENT PREPARATION OF BIOCARTOL ESTERS - SYNTHETIC AND STRUCTURAL INVESTIGATIONS IN THE (-)-2,2-DIMETHYL-3-FORMYLCYCLOPROPANE-1-CARBOXYLIC ACID SERIES

Authors
VEYRAT M FANTIN L DESMOULINS S PETITJEAN A MAZZANTI M RAMASSEUL R MARCHON JC BAU R
Citation
M. Veyrat et al., EN-ROUTE TO AN EFFICIENT PREPARATION OF BIOCARTOL ESTERS - SYNTHETIC AND STRUCTURAL INVESTIGATIONS IN THE (-)-2,2-DIMETHYL-3-FORMYLCYCLOPROPANE-1-CARBOXYLIC ACID SERIES, Bulletin de la Societe chimique de France, 134(7), 1997, pp. 703-711
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology,Chemistry
Journal title
Bulletin de la Societe chimique de France → ACNP
ISSN journal
00378968
Volume
134
Issue
7
Year of publication
1997
Pages
703 - 711
Database
ISI
SICI code
0037-8968(1997)134:7<703:ETAEPO>2.0.ZU;2-T
Abstract
Enantiopure eaters are obtained in good yield from (-)-2,2-dimethyl-3- formylcyclopropane-1-carboxylic acid (biocartol) in three steps: (1) d ithiane protection of the aldehyde function; (2) esterification of the carboxylic acid function; (3) dethioketalization. The X-ray structure s of biocartol and of its acetal 'dimer' are reported.