ANTIINFLAMMATORY EFFECTS OF RECOMBINANT HUMAN MANGANESE SUPEROXIDE-DISMUTASE ON ADJUVANT ARTHRITIS IN RATS

Authors
SHINGU M TAKAHASHI S ITO M HAMAMATU N SUENAGA Y ICHIBANGASE Y NOBUNAGA M
Citation
M. Shingu et al., ANTIINFLAMMATORY EFFECTS OF RECOMBINANT HUMAN MANGANESE SUPEROXIDE-DISMUTASE ON ADJUVANT ARTHRITIS IN RATS, Rheumatology international, 14(2), 1994, pp. 77-81
Citations number
23
Categorie Soggetti
Rheumatology
Journal title
Rheumatology international → ACNP
ISSN journal
01728172
Volume
14
Issue
2
Year of publication
1994
Pages
77 - 81
Database
ISI
SICI code
0172-8172(1994)14:2<77:AEORHM>2.0.ZU;2-I
Abstract
The anti-inflammatory effects of recombinant human manganese superoxid e dismutase on adjuvant arthritis was investigated. Local application of this manganese superoxide dismutase given every 2 days not only sig nificantly reduced foot swelling but also retarded radiological bone d estruction in adjuvant arthritis. Copper zinc superoxide dismutase had little effect on foot swelling.