FUTURE-DEVELOPMENTS IN THE TREATMENT OF IMMUNE-MEDIATED POLYNEUROPATHIES

The Guillain-Barre syndrome and chronic inflammatory demyelinating pol yneuropathy are the most extensively studied immune-mediated neuropath ies. Randomized treatment studies have been performed with corticoster oids, plasma exchange and more recently with high-dose immunoglobulins . In the future treatment may be more individualized based on specific immunological mechanisms. More immune-modulating treatments will beco me available also with recombinant DNA technology. This will offer new possibilities, but prior to the effective introduction of these new m olecules in the clinical setting, careful consideration and clinical t rials are required.