REACTIONS OF 6,6-DIALKYLFULVENES WITH 6-M ETHYL-2-PYRIDYLMETHYLLITHIUM AND 2-QUINOLYLMETHYLLITHIUM - SYNTHESIS OF NITROGEN-HETEROCYCLIC SUBSTITUTED FERROCENE DERIVATIVES
Zj. He et al., REACTIONS OF 6,6-DIALKYLFULVENES WITH 6-M ETHYL-2-PYRIDYLMETHYLLITHIUM AND 2-QUINOLYLMETHYLLITHIUM - SYNTHESIS OF NITROGEN-HETEROCYCLIC SUBSTITUTED FERROCENE DERIVATIVES, Huaxue xuebao, 55(6), 1997, pp. 605-610
In mixed tetrahydrogenfuran - ether solvent, exocyclic double bond add
ition reactions of 6, 6 - dialkylfulvenes or 6, 6 - polymethylenefulve
nes take place with 6 - methyl - 2 pyridylmethyllithium. When 6 - meth
yl - 6 -ethylfulvene or 6,6 - pentamethylenefulvene reacts with 2 - qu
inolylmethyllithium under similar conditions, addition and alpha - hyd
rogen abstract occur competitively. A series of nitrogen - heterocycli
c substituted ferrocene derivatives have been synthesized by complexat
ion of substituted cyclopentadienyllithium obtained in above reactions
with FeCl2. Their structures have been characterized by H-1 NMR, elem
ental analysis and mass spectra In their MS breakdown mechanism, coord
ination of pyridyl moiety to iron atom is proposed.