TESTICULAR RELAPSE OF ACUTE PROMYELOCYTIC LEUKEMIA AFTER ALLOGENEIC BMT

Authors
FORREST DL DALAL BI NAIMAN SC HORSMAN DE BERRY BR PARSLOW MI SINGH CP BENNY WB BARNETT MJ
Citation
Dl. Forrest et al., TESTICULAR RELAPSE OF ACUTE PROMYELOCYTIC LEUKEMIA AFTER ALLOGENEIC BMT, Bone marrow transplantation, 20(8), 1997, pp. 689-690
Citations number
10
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
20
Issue
8
Year of publication
1997
Pages
689 - 690
Database
ISI
SICI code
0268-3369(1997)20:8<689:TROAPL>2.0.ZU;2-Y
Abstract
After treatment of acute leukemia (typically ALL and the monocytic var iants of AML), relapse may occur at sites other than the marrow, Isola ted extramedullary relapse of acute promyelocytic leukemia (APL) howev er, is rare, We describe such an event in a man who underwent allogene ic BMT for APL in second relapse and 4 years later presented with test icular relapse, The marrow was morphologically and cytogenetically nor mal, but RT-PCR analysis revealed the specific PML/RAR chimeric RNA tr anscript.