SPONTANEOUS PNEUMOMEDIASTINUM IN A PATIENT WITH BRONCHIOLITIS OBLITERANS AFTER BONE-MARROW TRANSPLANTATION

After allogeneic bone marrow transplantation for chronic myelogenous l eukemia, spontaneous pneumomediastinum and subcutaneous emphysema deve loped in a patient with bronchiolitis obliterans. Computed tomography scanning of the chest failed to reveal the cause, There was no evidenc e of a pulmonary process, pneumothorax, or pharyngeal or upper airway leak, Despite the alarming appearance of the patient, conservative man agement, including high-flow oxygen, resulted in resolution of the pne umomediastinum and subcutaneous emphysema, The cause of pneumomediasti num and subcutaneous emphysema in bone marrow transplant recipients is discussed.