BLOOD-BANK LEUKOCYTE INFUSIONS AS REMISSION INDUCTION THERAPY IN A CASE OF ACUTE LYMPHOBLASTIC-LEUKEMIA

A 15-year-old female with pre-pre B ALL in third relapse was treated w ith administration of eight blood bank leukocyte concentrates per day for 5 days, The total number of mononuclear cells per kilogram of weig ht was 4.89 x 10(8). On the fifth day of infusions the patient was in complete remission (CR), asymptomatic and with a normal CBC, No second ary effects were found, The patient remained in CR without treatment f or 10 weeks before relapsing again, The possibility of reaching a shor t-lived, clinically relevant response, using blood bank leukocyte infu sions, is a promising new approach for the treatment of leukemia.