D. Klein et al., LYNGBYALOSIDE, A NOVEL 2,3,4-TRI-O-METHYL-6-DEOXY-ALPHA-MANNOPYRANOSIDE MACROLIDE FROM LYNGBYA-BOUILLONII (CYANOBACTERIA), Journal of natural products, 60(10), 1997, pp. 1057-1059
A novel 16-membered macrolide linked to a 2,3,4-tri-O-methyl-6-deoxy-a
lpha-mannopyranoside, lyngbyaloside (1), has been isolated from the bl
ue-green alga Lyngbya bouillonii, collected on Laing Island (Papua New
Guinea). Its structure has been established by a detailed high-field
2D NMR study. The relative configuration of 8 out of the 13 stereogeni
c carbon atoms is proposed from the analysis of NOE difference experim
ents.