SARCOID REACTION IN THYROID-DISEASES - REPORT OF A CASE OF THYROID-CARCINOMA DEMONSTRATING SARCOID REACTION IN REGIONAL LYMPH-NODES

We describe an extremely rare case of thyroid carcinoma accompanied by sarcoid reaction in regional lymph nodes. The patient, a 40-year-old woman, was found to have anterior neck swelling during a routine medic al examination. Physical examination revealed a bad movable and firm n odule measuring 3.5 x 2.5 cm in the right thyroid lobe. Examination of a fine-needle aspiration cytology of the nodule suggested papillary c arcinoma of class V. Right lobectomy and isthmectomy with neck dissect ion were performed. Histopathological examination of the resected spec imens revealed papillary carcinoma accompanied by metastatic foci in r ight perithyroidal lymph nodes and non-caseous sarcoidlike granulomas in pretracheal, right upper internal deep cervical and submandibular l ymph nodes. We concluded that these granulomas were due to a sarcoid r eaction associated with thyroid carcinoma, after performing examinatio ns to rule out the possibility of systemic sarcoidosis.