SYNTHESIS OF 6-AMINO-2-ARYL-4H-1-BENZOPYRAN-4-ONES

Synthesis of new mino-2-(substituted)-phenyl-4H-1-benzopyran-4-ones st arting from 4-acetamidophenol has been described. 5-Acetamido-2-hydrox yacetophenone on esterification with substituted aromatic acids using pyridine/POCl3 gave 2-aryloxyacetophenones which on Baker-Venkataraman rearrangement gave corresponding 1,3-diketones. The title compounds w ere obtained by cyclodehydration of 1,3-diketones in a mixture of etha nol and hydrochloric acid followed by neutralization of corresponding hydrochloride of 6-aminobenzopyrones.