Objective: The objective of the present study was to determine the pre
valence and characteristics of food cravings in women with a history o
f anorexia nervosa. Method: One hundred one control women selected at
random and 64 women with a diagnosis of anorexia nervosa 10 to 14 year
s earlier (cases) completed the Diagnostic interview for Genetic Studi
es, a food craving questionnaire, the Temperament and Character Invent
ory and the Three-Factor Eating Questionnaire. Results: A similar prop
ortion of cases and controls reported food cravings. A greater proport
ion of cases reported strong cravings with two or more features of int
ensity (p =.02). Cravings in the cases were more likely to be characte
rized by difficulty resisting the craved food (p =.0008), anxiety when
the craved food was unavailable (p = .002), and a high frequency of o
ccurrence (p =.007). The cases who craved were significantly more like
ly to have had lifetime BN (p =.02). Conclusion: A similar prevalence
of food craving in cases as in controls suggests that successful contr
ol of food intake and/or denial of hunger overrides dietary restrictio
n as a precondition for craving in anorexia nervosa. A dysfunction in
the serotonergic system, the provision of intermittent reinforcement b
y binge episodes, and/or frustration due to unsuccessful attempts at d
ietary restraint may mediate the association of cravings with the pres
ence of lifetime bulimia. (C) 1997 by John Wiley & Sons, Inc.