NOVEL AMPHIPHILIC LINEAR POLYMER DENDRIMER BLOCK-COPOLYMER - SYNTHESIS OF POLY(2-METHYL-2-OXAZOLINE) BLOCK POLY(AMIDO AMINE) DENDRIMER/

Novel linear polymer/dendrimer block copolymers, poly(2-methyl-2-oxazo line)-block-poly(amido amine) dendrimers (water-soluble full-generatio n type 4 (G = 4.0 and 5.0) and amphiphilic half-generation type 5 (G = 3.5, 4.5, and.5)), were synthesized by divergent-growth dendrimer con struction with omega-ethylenediamine-terminated poly(2-methyl-2-oxazol ine), which was prepared by living ring-opening polymerization of 2-me thyl-2-oxazoline. Assembly of the amphiphilic dendrimer-based block co polymer (G = 5.5) was investigated by surface tension measurements (cr itical micelle concentration, 0.49 wt.-%) and by small-angle neutron s cattering analysis (spherical particles; assembled number, ca. 10(3)).