PULMONARY INFILTRATION ASSOCIATED WITH MYELODYSPLASIA

Four case histories are reported in which the initial signs and sympto ms were those of pulmonary infiltration and in which subsequently a di agnosis of myelodysplasia was made. The analysis of bronchoalveolar la vage fluid - demonstrating predominantly neutrophils and lymphocytes, and, occasionally blast cells as well as plasma cells - indicated that the pulmonary infiltration was related to the myelodysplastic process . As no other causes of pulmonary infiltration could be found, it seem s that a pulmonary infiltrate can be the presenting symptom of a myelo dysplastic syndrome. Although pleuropulmonary infiltrates most often a re caused by infections, these cases illustrate that myelodysplasia re lated infiltrates should also be considered.