EXTRAMEDULLARY PLASMACYTOMA - REPORT OF A CASE DEVELOPED IN THE LARYNX

Extramedullary plasmacytoma is an uncommon tumor that usually arises i n the upper respiratory and/or digestive tract, although the larynx is the site least often involved. The submucosal location of the tumor m akes the diagnosis difficult, and most cases are identified late upon evaluation of nonspecific local symptoms. The diagnosis relies on immu nohistochemistry. Multiple myeloma differs radically from extramedulla ry plasmacytoma in terms of management and prognosis and should theref ore be definitely ruled out based on a set of converging clinical and radiological arguments. The management of laryngeal extramedullary pla smacytoma rests on surgery and/or radiation therapy. Follow-up should be prolonged since some patients develop locoregional recurrences or m ultiple myeloma.