Background: To present the laboratory portion of our first-semester Hu
man Neuroanatomy course at Temple University Medical School more effec
tively and efficiently and to replace the glass slide/microscope-based
laboratory component of the course, we developed a computer-based sub
stitute, Methods: For this computer-based neuroanatomy laboratory prog
ram, we photographed the (a) gross brain sliced and dissected specimen
s and (b) all the glass slides, from the sacral cord through the head
of the caudate nucleus, We digitized the photographed images and, usin
g Multimedia ToolBook (Asymetrix), created a computerized atlas, labor
atory guide, and a clinical problem-solving section, To assess the eff
ectiveness of the computerized laboratory, we compared student perform
ances between those classes that previously had the traditional labora
tory with two succeeding classes that used the computer-based laborato
ry, Results: Test score results of the laboratory portion of the cours
e suggested that performance on laboratory material was virtually unch
anged by the substitution of the computer program, By a survey taken a
t the end of the course, the students were very satisfied with the com
puterized program as a teaching method, Conclusions: The students and
faculty enthusiastically agreed that the computer program was an effec
tive substitute method for the traditional glass-slide laboratory and
that it was a beneficial self-educational tool that fostered independe
nt learning, The program encouraged student interaction and group lear
ning and fostered independence. It was a more efficient method for fac
ulty and students without sacrificing performance. (C) 1997 Wiley-Liss
, Inc.