CLINICAL-EVIDENCE FOR EFFECTIVENESS OF PHENCAL(TM) IN MAINTAINING WEIGHT-LOSS IN AN OPEN-LABEL, CONTROLLED, 2-YEAR STUDY

Over a 2-year period we carried out a prospective analysis of 247 outp atients in a very-low-calorie fasting program. Subjects having difficu lty attaining their desired weight or maintaining their desired weight constituted the experimental group. At 2 years, the experimental grou p that took the amino acid regimen of PhenCal(TM) com pared with the n on-PhenCal/Centrum(TM) vitamin control group showed a twofold decrease in percent overweight for both males and females; a 70% decrease in f ood cravings for females and 63% decrease for males; and a 66% decreas e in binge eating for females and 41% decrease for males. Most importa ntly, the experimental group (PhenCal group) regained only 14.7% of th e weight they lost during fasting while the control group (non-PhenCal group) regained 41.7% of the lost weight, and multiple regression mod eling revealed that with PhenCal treatment, morbid obesity and binge e ating score were significant predictors of weight gain after 2 years. In contrast, family history of chemical dependence was most closely as sociated, although not statistically significantly, with improved resu lts with PhenCal, These data suggest that PhenCal may be an anti-obesi ty adjunct.