DETERMINATION OF LEAD AND CADMIUM IN FOOD AND BLOOD BY INDUCTIVELY-COUPLED PLASMA-MASS SPECTROMETRY - A COMPARISON WITH GRAPHITE-FURNACE ATOMIC-ABSORPTION SPECTROMETRY
Zw. Zhang et al., DETERMINATION OF LEAD AND CADMIUM IN FOOD AND BLOOD BY INDUCTIVELY-COUPLED PLASMA-MASS SPECTROMETRY - A COMPARISON WITH GRAPHITE-FURNACE ATOMIC-ABSORPTION SPECTROMETRY, Science of the total environment, 205(2-3), 1997, pp. 179-187
To compare inductively coupled plasma mass spectrometry (ICP-MS) and g
raphite furnace atomic absorption spectrometry (GF-AAS) as the method
for determining lead and cadmium in the human diet and blood, 418 diet
homogenate samples and the same number of blood samples were collecte
d from Chinese and Japanese women and were analyzed by the two methods
. The results showed that our ICP-MS method is precise and accurate, b
eing comparable to the GF-AAS method established previously. The ICP-M
S method is simple and fast spending only one-tenth of the time necess
ary for GF-AAS and allows simultaneous analyses of lead and cadmium wi
th low detection limits. When applied to actual sample analysis, howev
er, ICP-MS results tend to be 10-20% lower than GF-AAS results in the
analysis of lead in the diet and blood and cadmium in blood. This is p
ossibly due to some interference in ICP-MS and matrix of samples. As t
he ICP-MS results could be mathematically corrected to be equivalent t
o the GF-AAS results, we conclude that this ICP-MS method can be used
as a routine analytical method for the determination of lead and cadmi
um in human diet and blood samples. (C) 1997 Elsevier Science B.V.