Th. Duong et al., REDUCED LOA-LOA MICROFILARIA COUNT 10 TO 12 MONTHS AFTER A SINGLE-DOSE OF IVERMECTIN, Transactions of the Royal Society of Tropical Medicine and Hygiene, 91(5), 1997, pp. 592-593
Citations number
12
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
The action of a single dose of ivermectin (200 mu g/kg) on 71 Gabonese
patients with Loa loa microfilariae in the peripheral blood, and livi
ng in areas highly endemic for loiasis, has been evaluated. Ten to 12
months after treatment, 43 patients (63%) had no circulating microfila
ria and the geometric mean peripheral blood microfilaria count had dec
reased by 88.6% (P<0.02). Thus, a single annual dose of ivermectin can
markedly reduce loiasis transmission.