AN IMPROVED OIL EMULSION SYNTHESIS METHOD FOR LARGE, POROUS ZIRCONIA PARTICLES FOR PACKED-BED OR FLUIDIZED-BED PROTEIN CHROMATOGRAPHY

Authors
ROBICHAUD MJ SATHYAGAL AN CARR PW FLICKINGER MC
Citation
Mj. Robichaud et al., AN IMPROVED OIL EMULSION SYNTHESIS METHOD FOR LARGE, POROUS ZIRCONIA PARTICLES FOR PACKED-BED OR FLUIDIZED-BED PROTEIN CHROMATOGRAPHY, Separation science and technology, 32(15), 1997, pp. 2547-2559
Citations number
15
Categorie Soggetti
Engineering, Chemical",Chemistry
Journal title
Separation science and technology → ACNP
ISSN journal
01496395
Volume
32
Issue
15
Year of publication
1997
Pages
2547 - 2559
Database
ISI
SICI code
0149-6395(1997)32:15<2547:AIOESM>2.0.ZU;2-7
Abstract
A previously reported oil emulsion technique for the synthesis of larg e, porous zirconia particles has been modified to overcome problems of nonreproducibility, formation of non-spherical or broken particles, a nd low yield of chromatographically useful particles. The improved tec hnique described here uses a concentrated sol and an in-line mixer to successfully solve these problems. The results indicate that the stirr ing rate used to maintain the emulsion during drying has a strong effe ct on the final particle size.