PERFORMANCE OF OPUS IMMUNOASSAYS FOR THYROXINE AND BETA-HUMAN CHORIONIC-GONADOTROPIN IN SERUM

Two representative immunoassays for measuring thyroxine and beta-subun it of human chorionic gonadotrophin in serum, using the Opus immunoass ay analyzer, were evaluated by comparing them to the reference RIA for T4 and beta-HCG enzyme immunoassay. Both assays were superior in accu racy and precision than the reference methods and exhibited good linea rity throughout the concentration range needed for discriminating abno rmally low and elevated concentrations from the established reference ranges of thyroxine and beta-human chorionic gonadotrophin in serum. C orrelation between the results of the Opus immunoassays and the refere nce assays for T4 and beta-HCG was very good with correlation coeffici ents of 0.92 and 0.98, respectively. (C) 1996 Wiley-Liss, Inc.