Left atrial myxomas are a rare stroke etiology (0.4 %). They frequentl
y present general symptoms such as fever, weight loss and an inflammat
ory syndrome, but the pseudolupic syndrome with cutaneous features and
vasomotor symptoms is rarely described. We report the case of a 38-ye
ar old man who presented in March 1995 a stroke caused by a left atria
l myxoma. There was also pseudolupic clinical and biological manifesta
tions which disapeared after ablation of the myxoma. Cerebral angiogra
phy showed a small carotid aspect which evoked carotid dissection or c
arotid siphon occlusion. The authors discuss neurologic and pseudolupi
c manifestations of left atrial myxomas, and their physiopathologic me
chanism.