P. Pawlowski et al., BIOELECTRORHEOLOGICAL MODEL OF THE CELL .7. CELLULAR-DEFORMATION IN THE PRESENCE OF CYTOCHALASIN-B, Biorheology, 34(3), 1997, pp. 171-193
The influence of cytochalasin B on the mechanical properties of Neuros
pora crassa cells subjected to a periodic electric field was investiga
ted Shear and extensional deformations were considered and studied sep
arately. Conditions were found under which shear deformations become i
rreversible. Rheologcal models helped in the interpretation of the res
ults in terms of the different response to the shear stress of the thr
ee hypothetical supramolecular regions of the membrane-skeleton networ
k (F, S and 0). Rheological parameters for the above regions related t
o the proposed models were calculated. The models were satisfactorily
fitted to the experimental results. The influence of cytochalasin B on
the course of extensional deformation of cells was investigated and c
haracterized semiquantitatively. (C) 1997 Elsevier Science Ltd.