LYMPHOCYTES PRODUCE SPECIFIC ALKALINE-PHOSPHATASE AFTER IN-VITRO STIMULATION OR AFTER IN-VIVO INFECTION WITH HIV-1

Authors
MURTHY VV
Citation
Vv. Murthy, LYMPHOCYTES PRODUCE SPECIFIC ALKALINE-PHOSPHATASE AFTER IN-VITRO STIMULATION OR AFTER IN-VIVO INFECTION WITH HIV-1, Journal of clinical laboratory analysis, 10(6), 1996, pp. 465-467
Citations number
10
Categorie Soggetti
Medical Laboratory Technology
Journal title
Journal of clinical laboratory analysis → ACNP
ISSN journal
08878013
Volume
10
Issue
6
Year of publication
1996
Pages
465 - 467
Database
ISI
SICI code
0887-8013(1996)10:6<465:LPSAAI>2.0.ZU;2-6
Abstract
A unique alkaline phosphatase isoform found in the serum of HIV-1 infe cted patients is thought to originate from CD4 lymphocytes. Destructio n of activated CD4 lymphocytes after HIV-1 infection is probably respo nsible for the appearance of this isoform in circulation. This band-10 alkaline phosphatase isoform is thus useful as an early marker for de tecting AIDS in children born to HIV-1 infected mothers. (C) 1996 Wile y-Liss, Inc.