ACCELERATION OF THE CONJUGATE ADDITION OF DIETHYL ZINC TO ENONES BY EITHER CU(OTF)(2) OR TRIVALENT PHOSPHORUS LIGANDS

Authors
ALEXAKIS A VASTRA J MANGENEY P
Citation
A. Alexakis et al., ACCELERATION OF THE CONJUGATE ADDITION OF DIETHYL ZINC TO ENONES BY EITHER CU(OTF)(2) OR TRIVALENT PHOSPHORUS LIGANDS, Tetrahedron letters, 38(44), 1997, pp. 7745-7748
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
44
Year of publication
1997
Pages
7745 - 7748
Database
ISI
SICI code
0040-4039(1997)38:44<7745:AOTCAO>2.0.ZU;2-Y
Abstract
The conjugate addition of diethyl zinc to enones under copper catalysi s occurs well with copper (II) triflate. Other copper salts need a pho sphine or phosphite ligand to be efficient. The best combination is co pper (II) triflate and triethyl phosphite. A very small amount of copp er (II) triflate (0.5%) and triehtyl phosphite (1%) are enough for hig h yields. (C) 1997 Elsevier Science Ltd.