HUMAN-HERPESVIRUS-6 INFECTION ASSOCIATED WITH ANTICONVULSANT HYPERSENSITIVITY SYNDROME AND REACTIVE HEMOPHAGOCYTIC SYNDROME

Authors
DESCAMPS V BOUSCARAT F LAGLENNE S ASLANGUL E VEBER B DESCAMPS D SARAUX JL GRANGE MJ GROSSIN M NAVRATIL E CRICKX B BELAICH S
Citation
V. Descamps et al., HUMAN-HERPESVIRUS-6 INFECTION ASSOCIATED WITH ANTICONVULSANT HYPERSENSITIVITY SYNDROME AND REACTIVE HEMOPHAGOCYTIC SYNDROME, British journal of dermatology, 137(4), 1997, pp. 605-608
Citations number
12
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
137
Issue
4
Year of publication
1997
Pages
605 - 608
Database
ISI
SICI code
0007-0963(1997)137:4<605:HIAWAH>2.0.ZU;2-Z
Abstract
Viral infections are thought to play a part in some cutaneous drug rea ctions, Human herpesvirus 6 (HHV6), which is the agent of exanthema su bitum (sixth disease), has never been implicated in a drug reaction. W e report a patient with severe phenobarbital-induced anticonvulsant hy persensitivity syndrome in whom a fulminant haemophagocytic syndrome w as associated with HHV6 infection. We discuss the possible role of HHV 6 in this reactive condition.