ASYMMETRIC NITROGEN .78. STERICALLY HINDERED INVERSION OF NITROGEN-ATOMS IN CYCLIC HYDRAZINES - N,N'-DIALKYL-1,3,4-OXADIAZOLIDINES, 1,3,4-THIADIAZOLIDINE, AND 4,5-BENZO-1,2,3,6-TETRAHYDROPYRIDAZINE

Authors
KOSTYANOVSKY RG RADEMACHER P ELNATANOV YI KADORKINA GK NIKIFOROV GA CHERVIN II USACHEV SV KOSTYANOVSKY VR
Citation
Rg. Kostyanovsky et al., ASYMMETRIC NITROGEN .78. STERICALLY HINDERED INVERSION OF NITROGEN-ATOMS IN CYCLIC HYDRAZINES - N,N'-DIALKYL-1,3,4-OXADIAZOLIDINES, 1,3,4-THIADIAZOLIDINE, AND 4,5-BENZO-1,2,3,6-TETRAHYDROPYRIDAZINE, Russian chemical bulletin, 46(7), 1997, pp. 1291-1299
Citations number
38
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
46
Issue
7
Year of publication
1997
Pages
1291 - 1299
Database
ISI
SICI code
1066-5285(1997)46:7<1291:AN.SHI>2.0.ZU;2-H
Abstract
N,N'-Diisopropyl-substituted 1,3,4-oxadiazolidine 3c, 1,3,4-thiadiazol idine 6, 4,5-benzo-1,2,3,6-tetrahydropyridazine 8, and new 3,4-dialkyl -1,3,4-oxadiazolidines 9-14 were synthesized and studied. The configur ational stability of the N atoms does not change on going from compoun d 3c to its S-analog 6 and decreases in the case of pyridazine 8. 3,4- Di-tert-alkyl-1 ,3,4-oxadiazolidines 3d and 11-14 were found to be pro mising objects for optical resolution.