INVASIVE HAEMOPHILUS-INFLUENZAE TYPE-B (HIB) INFECTION IN AN ADULT PATIENT WITH A SELECTIVE DEFICIENCY OF ANTIBODY TO THE HIB CAPSULAR POLYSACCHARIDE

Authors
FOLLIN P ULANOVA M HAHNZORIC M HANSON LA
Citation
P. Follin et al., INVASIVE HAEMOPHILUS-INFLUENZAE TYPE-B (HIB) INFECTION IN AN ADULT PATIENT WITH A SELECTIVE DEFICIENCY OF ANTIBODY TO THE HIB CAPSULAR POLYSACCHARIDE, Clinical infectious diseases, 25(4), 1997, pp. 915-917
Citations number
11
Categorie Soggetti
Microbiology,Immunology,"Infectious Diseases
Journal title
Clinical infectious diseases → ACNP
ISSN journal
10584838
Volume
25
Issue
4
Year of publication
1997
Pages
915 - 917
Database
ISI
SICI code
1058-4838(1997)25:4<915:IHT(II>2.0.ZU;2-0
Abstract
A 31-year-old woman without any underlying disease contracted severe i nvasive Haemophilus influenzae type b (Hib) infection but developed no antibodies to the Hib capsular polysaccharide. Serum immunoglobulin l evels were normal, but she had an isolated deficiency of antibody to H ib. Subsequently, immunization with a tetanus toxoid-conjugated Hib va ccine induced only a minimal response. However, she had a protective l evel of antibody (>1 mu g/mL) after the fifth vaccination.