STEREOSELECTIVE CYCLOPROPANATION WITH A SULTAM CARBENOID

Authors
HADDAD N GALILI N
Citation
N. Haddad et N. Galili, STEREOSELECTIVE CYCLOPROPANATION WITH A SULTAM CARBENOID, Tetrahedron : asymmetry, 8(20), 1997, pp. 3367-3370
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
20
Year of publication
1997
Pages
3367 - 3370
Database
ISI
SICI code
0957-4166(1997)8:20<3367:SCWASC>2.0.ZU;2-G
Abstract
Stereoselective cyclopropanation of alkenes with the Oppolzer's sultam carbenoid was examined for the first time. The addition reaction proc eeds in high yields on substituted alkenes and provides an easy access for stereoselective preparation of di-and tri-substituted cyclopropan es. The synthetic utility of the title reaction was demonstrated in th e stereoselective preparation of 1. (C) 1997 Elsevier Science Ltd.