THE TECHNETIUM WHITE CELL SCAN AS AN INITIAL IMAGING INVESTIGATION FOR EVALUATING SUSPECTED CHILDHOOD INFLAMMATORY BOWEL-DISEASE

Background: The technetium white cell scan (WCS) may be a useful inves tigation for patients with inflammatory bowel disease (IBD). In a retr ospective study we assessed the use of the WCS as an initial imaging i nvestigation in evaluating children with suspected IBD. Methods: Over a 3-year period, 60 WCS were performed on 55 patients (25 boys, median age 12.1 years, age range 1.5-18 years) with known or suspected IBD. There were two clinical groups: those with previously diagnosed IBD (h istologically and radiologically) and in clinical relapse (13 patients ), and newly presenting patients with suspected IBD (42 patients). Res ults: Eighteen scans were performed on the 13 patients presenting with relapse. Seventeen were positive and one patient, subsequently shown to have an inactive stricture, had a negative scan. Seven of the 42 ne wly presenting patients had abnormal scans, confirmed to be due to IBD by a combination of histology and barium examinations. Of the remaini ng 35 scans, three were abnormal and 32 were normal. None of these pat ients were subsequently proven to have IBD. These results show that in detecting active IBD, a positive WCS has a 100% sensitivity (24/24) a nd a 91% specificity (32/35) in the diagnosis of IBD. Conclusions: Our results show that the WCS is very useful as an initial imaging invest igation in evaluating patients with suspected IBD to select patients f or further investigation. (C) 1997 Lippincott-Raven Publishers.