The medical records of 20 patients undergoing revascularized jejunal f
lap reconstruction of hypopharyngeal defects were retrospectively revi
ewed to analyze the incidence of distal marginal recurrence, complicat
ion rates, and success of early functional restoration. This report is
one of few in the literature to address distal marginal recurrence in
patients undergoing jejunal free flap reconstruction of hypopharyngea
l defects. In 15 evaluable patients, two (13%) developed distal margin
al recurrences. Both patients had tumor involving the hypopharynx at t
he junction of the cervical esophagus. The major complication rate was
five of 20 patients (25%) and included three flap failures, one death
, and one intra-abdominal hemorrhage. The minor complication rate was
35%. The median hospital stay was 15.5 days and the median time to suc
cessful swallowing was 14.5 days. The functional success rate for swal
lowing was 58%. Because of the aggressive nature of this disease, we f
eel partial esophagectomy with jejunal flap reconstruction is warrante
d to achieve early functional restoration in a select group of patient
s when a 2-cm distal margin can be obtained above the cervical esophag
us with frozen-section control, and the distal esophagus is normal.