PERFECTLY BRANCHED POLYAMIDE DENDRONS BASED ON 5-(2-AMINOETHOXY)-ISOPHTHALIC ACID

Perfectly branched polyamide dendrons based on 5-(2-aminoethoxy)-isoph thalic acid have been synthesized up to generation 4 following the con vergent approach. This involved a repetitive reaction of 5-(2-t-butoxy carbamylethoxy)-isophthalic acid with the two fold excess of 5-(2-amin oethoxy-hydrochloride)-isophthalic acid dimethyl ester and its analogs of higher generation, respectively, using activation and protection m ethods from the peptide chemistry. The products were characterized via elemental analysis, different spectroscopic methods, gel permeation c hromatograpy, and differential scanning calorimetry. (C) 1997 Elsevier Science Ltd.