Treatment for postmenopausal osteoporosis should be offered to those w
ith a history of fractures following minimal trauma or with a bone den
sity significantly below the range seen in young normal adults. Underl
ying diseases contributing to the reduced bone density should be sough
t and treated appropriately. Lifestyle issues such as smoking, alcohol
intake and exercise should be addressed. A calcium intake of at least
1.5 g/day should be achieved. Hormone replacement therapy is the firs
t line pharmacological intervention. The bisphosphonates provide a sat
isfactory alternative for those unable or unwilling to take hormone re
placement therapy.