V. Zoete et al., DESIGN, SYNTHESIS AND ANTIOXIDANT PROPERTIES OF OVOTHIOL-DERIVED 4-MERCAPTOIMIDAZOLES, Journal of the Chemical Society. Perkin transactions. I, (20), 1997, pp. 2983-2988
Fourteen 4-mercaptoimidazoles derived from the naturally occurring fam
ily of antioxidants, the ovothiols, have been synthesized by cyclizati
on of thioamides with trimethylsilyl trifluoromethanesulfonate (trifla
te). These compounds have been assayed for their radical-scavenging ac
tivity.