RECIPROCAL RELATIONS BETWEEN THE LEVELS O F BETA-NGF, THYROXINE AND TESTOSTERONE IN MICE BLOOD-SERUM

Blood levels of (beta)-NGF, thyroxin and testosterone in mice were stu died to clear up their reciprocal relations. If was found that single injection of thyroxin (1,25 mg/g body weight (BW)) induced a sharp inc rease in serum NGF while testosterone (5mg/g BW) failed to produce any significant change during 24 hours-observation, Mice treated with NGF (10 mg/g BW) showed a 2,5 - fold elevation of blood serum thyroxin 6 h after injection followed by the recovery of the control value. Testo sterone slighly decreased in 6 h after injection and then increased in 12 h and 24 h. Both hormones, though not equally, influenced the cont ent of NGF in the sub-mandibular salivary gland and brain.