HEMATOPORPHYRIN DERIVATIVE OR PHTHALOCYAN INE PHOTOSENSITIZED HEMOLYSIS OF ERYTHROCYTES UNDER LASER IRRADIATION

Authors
KLEBANOV GI CHICHUK TV SHUTOVA LN STRANADKO EF VLADIMIROV YA
Citation
Gi. Klebanov et al., HEMATOPORPHYRIN DERIVATIVE OR PHTHALOCYAN INE PHOTOSENSITIZED HEMOLYSIS OF ERYTHROCYTES UNDER LASER IRRADIATION, Biologiceskie membrany, 14(5), 1997, pp. 486-494
Citations number
33
Categorie Soggetti
Cell Biology
Journal title
Biologiceskie membrany → ACNP
ISSN journal
02334755
Volume
14
Issue
5
Year of publication
1997
Pages
486 - 494
Database
ISI
SICI code
0233-4755(1997)14:5<486:HDOPIP>2.0.ZU;2-Q
Abstract
The effect of laser irradiation (LI) on the photosensitized (PHS) hemo lysis of rabbit erythrocytes was investigated. Two photosensitizers of domestic production were used: Photohem (hematoporphyrin derivate) an d Photosense (sulfonated phthalocyanine aluminium). The erythrocytes h emolysis was activated by LI in the presence of Photohem or Photosense . These process depended on the irradiation dose, photosensitizers con centration, and on the time of erythrocyte incubation with the photose nsitizers. Three lasers with wavelength of 520, 632,8, 850 nm were use d. It was found out that the PHS hemolysis of rabbit erythrocytes was inhibited by antioxidants.